Toxic Effects of Aqueous Extract of Two Medicinal Plants, Mansonia altissima and Sarcocephalus nervosus on Biochemical Indices of Clarias gariepinus (Burchell 1822)

  • Olusegun B. Samuel University of Lagos, Nigeria
  • Olajide O. Loto Olusegun Agagu University of Science and Technology Okitipupa, Nigeria
  • Julie T. Ojatuwase University of Lagos, Nigeria
Keywords: Acute toxicity, Aqueous extracts, Biochemical, Blood, Fish, Medicinal plants, Sub-lethal

Abstract

The acute and sub-lethal biochemical responses of Clarias gariepinus to aqueous extracts of Sarcocephalus nervosus (AESN) and Mansonia altissima (AEMA) were assessed through static renewal laboratory bioassays. The fish were exposed to sub-lethal doses (1/10th, 1/50th, 1/100th of 96h LC50) of AESN and AEMA for 21 days. The LC50 values for AESN were 30.71, 23.00, 15.81, and 13.36 g/L at 24, 48, 72, and 96 hours, respectively. No mortality occurred at 100 g/L of AEMA over 96 hours. ANOVA revealed significant differences (p<0.05) in mortality and biochemical responses; tissue levels of protein, cholesterol, triglycerides, and glucose, which ranged from 5.28 to 41.80 mg/dL, 18.46 to 89.35 mg/dL, 18.46 to 117.03 mg/dL, and 27.90 to 63.01 mg/dL, respectively. The study concluded that AESN and AEMA induce stress and significantly affect liver function, energy demand, and lipid metabolism in C. gariepinus.

Author Biographies

Olusegun B. Samuel, University of Lagos, Nigeria

Department of Marine Sciences, Faculty of Science

Olajide O. Loto, Olusegun Agagu University of Science and Technology Okitipupa, Nigeria

2Department of Fisheries and Aquaculture Technology

Julie T. Ojatuwase, University of Lagos, Nigeria

Department of Marine Sciences

Published
2022-08-30
How to Cite
Samuel, O. B., Loto, O. O., & Ojatuwase, J. T. (2022). Toxic Effects of Aqueous Extract of Two Medicinal Plants, Mansonia altissima and Sarcocephalus nervosus on Biochemical Indices of Clarias gariepinus (Burchell 1822). West African Journal of Fisheries and Aquatic Sciences, 3(1), 18-25. Retrieved from http://wajfas.unilag.edu.ng/article/view/2106
Issue
Vol 3 No 1 (2022)
Section
Research Articles

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